Incorrect genomic position for merged SNPs in release #23 data files
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[HapMap announcements] incorrect genomic position for merged SNPs in release #23 data files
This message is to inform you that the position of ~24,500 SNPs was
inadvertently entered incorrectly in HapMap release #23 bulk files
(genotypes and frequencies).The affected SNPs fall in the category of merged SNPs, which for this
release, consist of SNPs whose rs identifier in a previous dbSNP build
(NCBI build 35) were merged under new rs identifiers in dbSNP build 126
(NCBI build 36).A complete list of affected SNPs can be found here:
http://www.hapmap.org/genotypes/2008-01/positional_errors/
The format of the above list(s) consist of merged rsid, incorrect
(ncbi_b35) and corrected (ncbi_b36) position (strand is also given in
parenthesis, if affected by this glitch).We emphasize that GENOTYPES ARE NOT AFFECTED by this glitch.
Only chromosomal position (ncbi_b35 coordinates given instead of
ncbi_b36 coordinates) were affected. In consequence, determination of
reference allele for allele/genotype frequency calculations may have
also been affected, as well as strand orientation in a handful of cases
(18-23 SNPs).All errors are being corrected in NEW genotypes and frequency files,
which will be made available shortly as a new HapMap release #23a.Our sincere apologies for any inconvenience this may have caused you.
